Ph. D. Project
Title:
Social cognition in low grade glioma
Dates:
2024/04/09 - 2027/03/31
Student:
Supervisor(s):
Description:
Diffuse low grade glioma (DLGG) are a specific disease between oncology and neurosciences.
Troubles in social cognition have been few studied. There are nevertheless frequent and might have a negative
impact on the global cognitive functioning by slowing the socioprofessional rehabilitation. Those troubles might
degrade the quality of life of patients. We propose here to 1/study the evolution of the trouble in social
cognition in a population of patients followed for a DLGG by focusing on mentalization and prosody 2/correlate
those troubles with quality of life at each step of the disease 3/ assess the neural basis of mentalization and
prosody.
We make the hypothesis that patient with best performance in social cognition have a better score in quality of
life and that some treatment might alter the studied parameters (radiotherapy) whereas other might preserve
or improve them (surgery, chemotherapy, targeted therapy).
Troubles in social cognition have been few studied. There are nevertheless frequent and might have a negative
impact on the global cognitive functioning by slowing the socioprofessional rehabilitation. Those troubles might
degrade the quality of life of patients. We propose here to 1/study the evolution of the trouble in social
cognition in a population of patients followed for a DLGG by focusing on mentalization and prosody 2/correlate
those troubles with quality of life at each step of the disease 3/ assess the neural basis of mentalization and
prosody.
We make the hypothesis that patient with best performance in social cognition have a better score in quality of
life and that some treatment might alter the studied parameters (radiotherapy) whereas other might preserve
or improve them (surgery, chemotherapy, targeted therapy).
Keywords:
social cognition, quality of life, diffuse low grade glioma, prosody, theory of mind
Department(s):
| Biology, Signals and Systems in Cancer and Neuroscience |