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TZID:Europe/Paris
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UID:619@cran.univ-lorraine.fr
DTSTART;TZID=Europe/Paris:20241202T130000
DTEND;TZID=Europe/Paris:20241202T140000
DTSTAMP:20241122T122847Z
URL:https://www.cran.univ-lorraine.fr/events/seminaire-de-inga-saknite/
SUMMARY:Séminaire de Inga Saknite
DESCRIPTION:Speaker: Inga Saknite\, Biophotonics Laboratory\, University of
  Latvia (Riga\, Latvia)\, Vanderbilt University Medical Center (Nashville\
 , Tennessee\, USA)\nTitle: Bedside videomicroscopy of blood cell dynamics 
 in skin microvasculature for clinical impact\nLocation: Room ED38\, Buildi
 ng E\, Faculty of Medicine\, Brabois-Santé Campus - Teams link\n\nAbstrac
 t: Cutaneous microcirculation regulates the exchange of nutrients\, heat a
 nd inflammatory cells between blood and tissue\, and plays a significant r
 ole in many diseases\, including cancer and hypersensitivity reactions. Vi
 sualization of individual cell motion in a single cutaneous blood vessel m
 ay further enhance our understanding of disease pathology and enable the d
 evelopment of novel biomarkers. In this study\, we characterized individua
 l cell motion in the upper dermal microvasculature of healthy human skin b
 y noninvasive reflectance confocal video microscopy. In addition to visual
 izing previously described adherent and rolling leukocytes\, we visualized
  temporary stopping of leukocytes (“paused” leukocytes) in human skin 
 microvasculature\, which has been previously described in a broad range of
  animal species (also referred to as plugging\, stopping\, trapping or ret
 aining of leukocytes). This work provides new insights into cell dynamics 
 in intact human skin blood vessels. Through the detailed data acquisition 
 protocol and method to extract quantitative parameters from reflectance co
 nfocal videos\, this study will enable further exploration of the diagnost
 ic potential for various clinical applications.\n\nBiography: Dr. Saknite 
 received her PhD in physics from the University of Latvia in 2016. She was
  then awarded the Fulbright Scholarship to advance her translational resea
 rch career at the Beckman Laser Institute of the University of California\
 , Irvine. From 2017 until 2021\, Dr. Saknite was a Postdoctoral Research F
 ellow at the Vanderbilt Dermatology Translational Research Clinic (VDTRC.o
 rg)\, and was named the inaugural Vanderbilt Postdoctoral Mentor of the Ye
 ar in 2021. She has received several additional awards\, including the Abs
 tract Achievement Award at the Annual Meeting of the American Society of H
 ematology and the best talk award at the Annual Vanderbilt Postdoctoral As
 sociation Symposium. In 2024\, she became a Senior Member of SPIE\, the in
 ternational society for optics and photonics.\n\nLa visite de Inga Saknite
  est financée par le programme Osmose (Campus France) et est intégrée a
 u programme interdisciplinaire MAT-PULSE (LUE).
CATEGORIES:Département BioSiS,Séminaires projet PhotoDiag
LOCATION:Faculté de médecine - Brabois-Santé\, 9\, Avenue de la Forêt d
 e Haye\, Vandoeuvre-lès-Nancy\, France
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=9\, Avenue de la Forêt de 
 Haye\, Vandoeuvre-lès-Nancy\, France;X-APPLE-RADIUS=100;X-TITLE=Faculté 
 de médecine - Brabois-Santé:geo:0,0
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TZID:Europe/Paris
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DTSTART:20241027T020000
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