Subject Ph. D.

Diffuse low grade glioma (DLGG) are a specific disease between oncology and neurosciences. Troubles in social cognition have been few studied. There are nevertheless frequent and might have a negative impact on the global cognitive functioning by slowing the socioprofessional rehabilitation. Those troubles might degrade the quality of life of patients. We propose here to 1/study the evolution of the trouble in social cognition in a population of patients followed for a DLGG by focusing on mentalization and prosody 2/correlate those troubles with quality of life at each step of the disease 3/ assess the neural basis of mentalization and prosody. We make the hypothesis that patient with best performance in social cognition have a better score in quality of life and that some treatment might alter the studied parameters (radiotherapy) whereas other might preserve or improve them (surgery, chemotherapy, targeted therapy).